The beginning of the formation of the garrison hospital complex dates back to the second half of the XVIII century.
In 1794, according to the project of architect Alexander Guchev, a two-story stone building was built to accommodate dragoon teams in the area of the earthen rampart. In the 1830s, the building was radically rebuilt to accommodate the garrison hospital, possibly designed by architect P.I. Praman. At the same time, stone and wooden buildings of medical services were erected along the perimeter of the courtyard. The building of the garrison hospital is arranged according to a corridor system with a grand staircase and a lobby.
This is how the city hospital is described in the newspaper "Tobolsk Provincial Vedomosti": "The Tobolsk City Hospital is located in a separate three-storey house located on a mountain, in a healthy and elevated area, with a large lime garden and completely isolated from neighboring residential buildings.
The men’s department consists of ten wards on the third floor; the height of the wards is 6 ½ arshins. Patients with rash, syphilitic, ocular, typhoid and difficult — have their own separate wards, as well as surgical patients. The women’s department is located in seven separate rooms on the second floor; each ward is 6 ½ arshins high and 10 ½ arshins long." (Tobolsk provincial Gazette. 1882. No. 36. pp. 2−4).
On the ground floor of the hospital, in a separate large ward, sick crazy women were placed. The male lunatics were housed in a separate building, which had previously been occupied by an orphanage with a separate garden.
Until 1884, there was an orphanage at the hospital, in which there were 15 children, with them there was a matron, four maids and a laundress. In 1884, the orphanage was closed, and all the children were given to private individuals for upbringing.
In 1895, a house church was built in the hospital building in the name of the icon of the Mother of God "Joy to All Who Mourn". For a long time, the priest of the hospital church was Nikolai Pavlovich Bellavin.
The completion of the hospital complex dates back to the end of the XIX century, when a two-story brick building was built in the northern part of the estate.
In 1911, the hospital was headed by senior physician Vladimir Karlovich Lindenberg. Columnists of the newspapers "Tobolsk Provincial Vedomosti" and "Siberian Leaf" described the doctors' service as hard and necessary work.
In Soviet times, the building was used as a medical institution, there was a therapeutic department of the city hospital.
After the completion of repair and restoration work, the city administration was located in it.