The street is named so from the village of Zashchitina Bronnikova parish of Tobolsk county, which was located north of Tobolsk down the Irtysh. Originally the village was called Zashchita (Protection).
All sources point to the founding of the village only in the XVIII century. The village is not mentioned in the "Drawing Book" by S.U. Remezov. Historian Gerard Miller in 1739−1741 did not single out the village of Protection as a separate settlement, considering it a suburb of Tobolsk.
According to historian N.A. Balyuk, the foundation of the village should be attributed to the second half of the XVIII century. By the decree of the Governor D.I. Chicherin, 14 exiles were assigned to Zashchita.
In 1868, there were 11 courtyards in the village of Zashchitina Bronnikovskaya volost, 54 residents lived (28 m., 26 w.). Public figures of Tobolsk noted in the village the infertility of the land and the lack of clean drinking water.
According to the first All-Russian Population Census, in 1897 there were 19 households and 76 inhabitants in the village of Zashchitina Bronnikovskaya volost. The namesake composition of the population is very motley: Vasilievs, Vokhmintsev, Ilyins, Savins, Levichevs, Anikins, Sargins, Samarokovs, Tulipovs. The most numerous peasant surnames are the Zakharovs (4 families), the Abramovs and the Mikhailovs (2 families each). The inhabitants were engaged in agriculture, weaving, and the manufacture of jewelry. Peasant Ivan Pavlovich Sargin with his son Andrey, Gavrila Pavlovich Vokhmintsev, Nikolai Grigoryevich Anikin and Alexey Mikhailovich Mikhailov served as coachmen.
The close proximity of Zashchitina to the city allowed residents to look for sources of income in Tobolsk. For example, the Tulipov and Mashkarov families were listed in Zashchita, but lived and worked in the city.
In 1926, in the village of Zashchitina of the Verkhne-Filatov Village Council there were 17 courtyards, 96 residents lived.
Currently, the village of Zashchitina in the northern part of Tobolsk is called the neighborhood "Zashchitino".